Jonas Knoch

Education

Practicals

• Tutorials for lecture “Engineering Mathematics” (SS 19)
• Tutorials for lecture “Mathematik für Ingenieure E3” (WS 18/19)
• Tutorials for lecture “Mathematik für Ingenieure E2” (SS 18)
• Tutorials for lecture “Mathematik für Ingenieure E1” (WS 17/18)
• Tutorials for lecture “Genomanalyse und Phylogenie” (WS 16/17)
• Tutorials for lecture “Stochastische Modelle” (WS 16/17)

Sepsis is defined as systemic inflammation in the presence of an infection and is number three cause of mortality in the general population. Early and systematic treatment of sepsis is often crucial for the survival of patients, but unfortunately, a correct and fast diagnosis is still challenging for physicians. With the goal to gain a better understanding of cellular processes during sepsis, the “SCIDATOS“-project (Scientific Computing for the Improved Detection and Therapy of Sepsis) was founded as collaboration of the University Medical Center Mannheim and the Interdisciplinary Center for Scientific Computing in Heidelberg in 2016. Within the framework of this project, Jonas deals with the modeling, analysis and simulation of metabolic reaction networks of cells. In particular, the focus is on how the metabolism behaves in septic tissues, which are often characterized by low oxygen tension.