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Jonas Knoch

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Jonas Knoch

Jonas Knoch

Jonas Knoch, M. Sc.

Jonas Knoch

Department of Mathematics
Chair of Applied Mathematics (Modeling and Numerics) (Prof. Dr. Burger)

Room: Raum 04.336
Cauerstraße 11
91058 Erlangen
  • Phone number: +49 9131 85-67212
  • Fax number: +49 9131 85-67225
  • Email: jonas.knoch@fau.de

Research interests:

  • Modeling, analysis and simulation of metabolic pathways
  • Parameter estimation and sensitivity analysis of mathematical models

Jonas Knoch is member of the research group AG Neuss-Radu.

Curriculum Vitae

Education

2017–2019 Master’s studies in Integrated Life Sciences, FAU Erlangen-Nürnberg
2014–2017 Bachelor’s studies in Integrated Life Sciences, FAU Erlangen-Nürnberg
2014 Abitur at Arnold-Gymnasium Neustadt bei Coburg

Practicals

  • Tutorials for lecture “Engineering Mathematics” (SS 19)
  • Tutorials for lecture “Mathematik für Ingenieure E3” (WS 18/19)
  • Tutorials for lecture “Mathematik für Ingenieure E2” (SS 18)
  • Tutorials for lecture “Mathematik für Ingenieure E1” (WS 17/18)
  • Tutorials for lecture “Genomanalyse und Phylogenie” (WS 16/17)
  • Tutorials for lecture “Stochastische Modelle” (WS 16/17)

Research

Sepsis is defined as systemic inflammation in the presence of an infection and is number three cause of mortality in the general population. Early and systematic treatment of sepsis is often crucial for the survival of patients, but unfortunately, a correct and fast diagnosis is still challenging for physicians. With the goal to gain a better understanding of cellular processes during sepsis, the “SCIDATOS“-project (Scientific Computing for the Improved Detection and Therapy of Sepsis) was founded as collaboration of the University Medical Center Mannheim and the Interdisciplinary Center for Scientific Computing in Heidelberg in 2016. Within the framework of this project, Jonas deals with the modeling, analysis and simulation of metabolic reaction networks of cells. In particular, the focus is on how the metabolism behaves in septic tissues, which are often characterized by low oxygen tension.

Publications

2020

  • Bocharov G., Jäger W., Knoch J., Neuss-Radu M., Thiel M.:
    A Mathematical Model of HIF-1 Regulated Cellular Energy Metabolism
    In: Vietnam Journal of Mathematics (2020)
    ISSN: 0866-7179
    DOI: 10.1007/s10013-020-00426-y
    BibTeX: Download
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91054 Erlangen
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